Letrozole - Femara
Letrozole (most common brand name – Femara) is an Aromatase Inhibitor (AI). Therefore, this is an anti-estrogen.
Letrozole available forms are as a tablet or as an oral solution.
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Femara (Letrozole) is helpful in controlling estrogen related issues. In medical issues, it’s used for treating breast cancer in postmenopausal women. However, Letrozole in medical settings is also used for inducing ovulation in women. Moreover, you could find it prescribed for pretreatment for termination of pregnancy in combination with other drugs, for treatment of gynecomastia, for promoting spermatogenesis, for treatment of endometriosis, and various others.
Anyway, those men with high estrogen related issues usually use Letrozole with a high success rate. In case estrogen levels increase more than the normal range (due to health conditions or using whatever medications) and cause some side effects – Letrozole is helpful. That’s because Letrozole is the most powerful aromatase inhibitor (AI) out there – it inhibits aromatization. This is the process of converting testosterone into estrogen. As a result, total estrogen levels decreases.
Selective Estrogen Receptor Modulators (SERMs) are also anti-estrogens. However, they selectively bind to estrogen receptors. Letrozole is binding to aromatase enzymes and disables them. It lowers total estrogen levels by reducing aromatization. That’s why Letrozole is an extremely effective product for those suffering from high-estrogen related symptoms. Many consider it to be the most effective stuff against gynecomastia. Because it’s the most powerful Aromatase Inhibitor (AI) lowering estrogen levels like no other AI. So, this is a great option for men who want to avoid water retention, gynecomastia, erectile dysfunction, and many other issues related to estrogen. But often it turns out to suppress estrogen too much because of how drastically it lowers estrogen.
That’s the biggest reason why Letrozole (Femara) is popular among men using PEDs (Performance Enhancing Drugs). For lowering estrogen and preventing/treating estrogen-related symptoms. It won’t allow testosterone to convert into estrogen because would block aromatization. Thus, lower estrogen.
Nevertheless, in medical settings, the drug is mainly offered to postmenopausal women for preventing and treating breast cancer. Might be helpful for many other health conditions too such as treating endometriosis, azoospermia, pretreatment of pregnancy termination, and various others.
